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REF DUPL: Tacrolimus
Predict NMR spectrum
RN: 
104987-11-3
MF: 
C44H69NO12
MW: 
804.03136
InChI:  1S/C44H69NO12/c1-10-13-31-19-25(2)18-26(3)20-37(54-8)40-38(55-9)22-28(5)44(52,57-40)41(49)42(50)45-17-12-11-14-32(45)43(51)56-39(29(6)34(47)24-35(31)48)27(4)21-30-15-16-33(46)36(23-30)53-7/h10,19,21,26,28-34,36-40,46-47,52H,1,11-18,20,22-24H2,2-9H3/b25-19-,27-21+/t26-,28+,29+,30-,31+,32-,33+,34-,36+,37-,38-,39+,40+,44+/m0/s1
InChIKey:  QJJXYPPXXYFBGM-LJIGMGMYSA-N
H donor:  3
H acceptor:  13
Rotatable bond:  7
Stereocenter:  14
cLogP:  5.514
cLogS:  -5.676
Polar surface:  178.36
Permanent link: http://www.chemexper.com/search/cas/104987113.html Report error(s)
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  Supplier     Description     Reference  
bocsci Tacrolimus, >98%
on request
amadischem Tacrolimus, 98%
Bulk, semi-bulk
capotchem Tacrolimus, 97%(Min,HLPC)
5kg
25kg
100kg
200kg
tons
1kg
advtechind tacrolimus,99%
1G
advtechind tacrolimus, usp standard
150MG
alfa-chemistry Tacrolimus (also FK-506 or fujimycin, trade names Prograf, Advagraf, Protopic) is an immunosuppressive drug used mainly after allogeneic organ transplant to lower the risk of organ rejection. It achieves this by inhibiting the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, which are vital to the body’s learned (or adaptive) immune response.Tacrolimus is also used in the treatment of other T cell-mediated diseases such as eczema (for which it is applied to the skin in a medicated ointment), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, Kimura’s disease, and the skin condition vitiligo.Chemically it is a 23-membered macrolide lactone that was first discovered in 1987 from the fermentation broth of a Japanese soil sample that contained the bacterium Streptomyces tsukuba, 98%+
25g
100g
250g
1g
5g
10g
leapchem tacrolimus, 98%
on request
leapchem tacrolimus
on request
leapchem tacrolimus
on request
aifchem (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 98%
250mg
5g
25g
cm-finechemicals FK506
Research
Pilot
lclabs FK-506
50 mg
100 mg
200 mg
500 mg
1 g
2 g
5 g
advtechind tacrolimus, 98.5%
1G
chemcube
Tacrolimus
 , >98%
on request
carbonesci Tacrolimus, 98%
on request
lingruichem Tacrolimus
on request
oakwood
Tacrolimus
10mg
rovathin
Tacrolimus
 , 98%
on request
biosynth
Tacrolimus monohydrate
on request
yuansu-reagent Tacrolimus

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